YAP1 - meaning and definition. What is YAP1
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What (who) is YAP1 - definition


YAP1         
  • Modular Structure of YAP1 Isoforms
  • On the left, the signaling cascade is inactivated so YAP readily localizes to the nucleus for transcription. On the right, the signal cascade causes YAP to localize to the cytoplasm, preventing transcription.
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
YAP1 (gene); YAP (protein)
YAP1 (yes-associated protein 1), also known as YAP or YAP65, is a protein that acts as a transcription coregulator that promotes transcription of genes involved in cellular proliferation and suppressing apoptotic genes. YAP1 is a component in the hippo signaling pathway which regulates organ size, regeneration, and tumorigenesis.